conditioning chambers with standard sound attenuation (Coulbourn Instruments)
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Conditioning Chambers With Standard Sound Attenuation, supplied by Coulbourn Instruments, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/conditioning+chambers+with+standard+sound+attenuation/conditioning+chambers+with+standard+sound+attenuation/pm37776946-71-2-13
Average 90 stars, based on 1 article reviews
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other:Article Title: 5-HT 6 Receptors Control GABAergic Transmission and CA1 Pyramidal Cell Output of Dorsal Hippocampus. Article Snippet: The blockade of 5-HT6 receptors represents an experimental approach that might ameliorate the memory deficits associated with brain disorders, including Alzheimer’s disease and schizophrenia.. However, the synaptic mechanism by which 5-HT6 receptors control the GABAergic and glutamatergic synaptic transmission is barely understood.. In this study, we demonstrate that pharmacological manipulation of 5-HT6 receptors with the specific agonist EMD 386088 (7.4 nM) or the antagonist SB-399885 (300 nM) modulates the field inhibitory postsynaptic potentials of the dorsal hippocampus and controls the strength of the population spike of pyramidal cells. |
![vHPC‐PL pathway stimulation effects on contextual fear expression. (a) Top, experimental design of the compound ABCA fear renewal protocol. Optogenetic stimulation of the vHPC‐PL pathway took place during the baseline pre‐CS presentation periods in both renewal test sessions. All sessions took place on different days. Bottom, comparison of the average time spent freezing during the different learning stages of the protocol for the stimulated animals (ChR2, n = 7) and controls ( n = 7). Whiskers depict ±SEM, the shaded blue rectangle indicates when laser was ON. [n.s.: no significant difference between groups; *: t (12) = 2.51, p = 0.027; unpaired t ‐test, see Section and Data ]. (b) Top, experimental design of the contextual fear <t>conditioning</t> and recall test protocol. Bottom, comparison of percentage of time spent freezing during the baseline and the inter‐trial intervals (ITI) of the contextual fear conditioning session (left) and during the 6 min of the contextual fear recall test (right) for the laser stimulated group ( n = 9) and control animals ( n = 19). Whiskers depict ±SEM, the shaded blue rectangle indicates when laser was ON. [No significant difference at any time point; unpaired t ‐test, see Section and Data ]. (c) Top, experimental design of the ABA fear renewal protocol. Below, comparison of the average time spent freezing during the different learning stages of the protocol for the stimulated animals (ChR2, n = 10) and controls ( n = 18). Same format as panels (a) and (b). CS 1–4 = average freezing over the first four CS presentations. [*: t (24) = 2.80, p = 0.010; unpaired t ‐test, see Section and Data ]](https://pub-med-central-images-cdn.bioz.com/pub_med_central_ids_ending_with_8305/pmc12548305/pmc12548305__EJN-62-0-g001.jpg)